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cetrocetrorelix acetate

cetrocetrorelix acetate

CAS Number: 120287-85-6

Formula: C72H96ClN17O16

Molecular Weight : 1491.1 g/mol

 Method of Analysis:In House

Pharmacology : Cetrorelix  or cetrorelix acetate sold under the brand name Cetrotide, is an injectablegonadotropin-releasing hormone (GnRH) antagonist. A synthetic decapeptide, it is used in assisted reproduction to inhibit premature luteinizing hormone surges[1] The drug works by blocking the action of GnRH upon the pituitary, thus rapidly suppressing the production and action of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). In addition, cetrorelix can be used to treat hormone-sensitive cancers of the prostate and breast (in pre-/perimenopausal women) and some benign gynaecological disorders (endometriosis, uterine fibroids and endometrial thinning). It is administered as either multiple 0.25 mg daily subcutaneous injections or as a single-dose 3 mg subcutaneous injection. The duration of the 3 mg single dose is four days; if human chorionic gonadotropin (hCG) is not administered within four days, a daily 0.25 mg

dose is started and continued until hCG is administered.

Mechanism:Cetrorelix is a man-made hormone that blocks the effects of Gonadotropin Releasing Hormone (GnRH). GnRH controls another hormone that is called luteinizing hormone (LH), which is the hormone that starts ovulation during the menstrual cycle. When undergoing hormone treatment sometimes premature ovulation can occur, leading to eggs that are not ready for fertilization to be released. Cetrorelix does not allow the premature release of these eggs to occur.

For the inhibition of premature LH surges in women undergoing controlled ovarian stimulation

Storage Condition: Store at a temperature of  2-8ᵒC.Protected from light

Packaging: Vial