Tofigh Daru’s Chemistry R & D laboratories, which were launched in 2004, aim to define new missions in the advancement of API Industry.
This department plays an integral role for the company benefiting from the knowledge and competence of a large number of experienced specialists aiming at the ultimate goals of the company to acquire technological development and optimization, and employing the facilities required for manufacturing of high-quality products. Moreover, it is intended to increase the productivity through continuous improvement of processes and turning technical know-how into wealth. The company has been successful to accomplish projects listed below:
Selecting the latest and most effective active pharmaceutical ingredients and creating technical know-how to produce them
Synthesizing laboratory-scale active pharmaceutical ingredients and developing them in the large scale
Offering technical support for manufacturing difficulties and development of technical solutions
Transferring technical know-how for manufactured products to the other companies
Providing theoretical services for selection and development of pharmaceutical compounds
Accomplished technical know-how projects in the field of manufacturing active pharmaceutical ingredients are as follows:
Atracurium Besilate
Aprepitant
Aripiprazole
Alprazolam
Alfentanil Hydrochloride
Imatinib Mesylate
Imipramine
Baclofen
Tolterodine Tartrate
Prasugrel Hydrochloride
Dabigatran Etexilate Mesylate
Desipramine
Deferasirox
Dimethyl Fumarate
Remifentanil Hydrochloride
Rivastigmine Hydrogen Tartrate
Rivaroxaban
Zoledronic Acid
Sodium Valproate
Sitagliptin Phosphate Monohydrate
Cinacalcet Hydrochloride
Sufentanil Citrate
Fluvoxamine Maleate
Fentanyl Citrate
Fenofibrate
Fingolimod Hydrochloride
Letrozole
Clopidogrel
Clomipramine
Clonazepam
Gabapentin
Glatiramer Acetate
Mesalazine
Memantine Hydrochloride
The reactions that we are expert at:
Enantiomers Separation
Reduction
Oxidation
N-alkylation
O-alkylation
N- demethylation
N- debenzylation
Amidation
Esterification
Coupling reactions
Nitration
Cyclization
Isomerization
Grignard reactions
Oxime Synthesis
Polymerization
