CAS Number: 1239908-20-3

Formula:  C20H23BCl2N2O9

 Molecular Weight : 517.12 

Method of Analysis: In house

Application:

Multiple Myeloma (MM)

Mechanism:

Ixazomib induced apoptosis of multiple myeloma cell lines in vitro. Ixazomib demonstrated in vitro cytotoxicity against myeloma cells from patients who had relapsed after multiple prior therapies, including bortezomib, lenalidomide, and dexamethasone. The combination of ixazomib and lenalidomide demonstrated synergistic cytotoxic effects in multiple myeloma cell lines. In vivo, ixazomib demonstrated antitumor activity in a mouse multiple myeloma tumor xenograft model.

Storage conditions:

Store in well closed container at 2-8ᵒC

Packaging:

The final product is packed in polyethylene nylon plastic bag and then packaged in a 3-layered aluminum foil.