CAS Number: 960404-48-2 

Formula: C24H35ClO9 

Molecular Weight: 502.99

  Method of Analysis: In House 

Application: 

Type 2 Diabetes Mellitus 

Mechanism 

Sodium-glucose cotransporter 2 (SGLT2), expressed in the proximal renal tubules, is responsible for the majority of the reabsorption of filtered glucose from the tubular lumen. Dapagliflozin is an inhibitor of SGLT2. By inhibiting SGLT2, dapagliflozin reduces reabsorption of filtered glucose and thereby promotes urinary glucose excretion. Dapagliflozin also reduces sodium reabsorption and increases the delivery of sodium to the distal tubule. This may influence several physiological functions including, but not restricted to, lowering both pre-and afterload of the heart and downregulation of sympathetic activity, and decreased intraglomerular pressure which is believed to be mediated by increased tubuloglomerular feedback

Storage conditions: 

Preserve in well-closed, light resistance containers. Store at controlled room temperature.

     Packaging 

The final product is packed in polyethylene nylon plastic bag and then packaged in a 3-layered aluminum foil.