CAS Number: 124937-52-6 

Formula: C26H37NO7

Molecular Weight: 475.5745

Method of Analysis: In House 

Application: 

Urinary Urge Incontinence

Mechanism 

Tolterodine acts as a competitive antagonist of acetylcholine at postganglionic muscarinic receptors. Both urinary bladder contraction and salivation are mediated via cholinergic muscarinic receptors. After oral administration, tolterodine is metabolized in the liver, resulting in the formation of 5- hydroxymethyl tolterodine (5-HMT), the major pharmacologically active metabolite. 5-HMT, which exhibits an antimuscarinic activity similar to that of tolterodine, contributes significantly to the therapeutic effect. Both tolterodine and 5-HMT exhibit a high specificity for muscarinic receptors, since both show negligible activity or affinity for other neurotransmitter receptors and other potential cellular targets, such as calcium channels.

Storage conditions: 

Preserve in well-closed containers. Store at room temperature. 

     Packaging 

The final product is packed in polyethylene nylon plastic bag and then packaged in a 3-layeredaluminum foil.