Sufentanil is a synthetic, potent opioid with highly selective binding to mu-opioid receptors. Sufentanil acts as a full agonist on these receptors and does not induce histamine release. It is 5-10 times more potent than fentanyl and is the most potent opioid. However, it has a shorter duration of action. Sufentanil has a high lipid solubility, which accounts for the fast onset when given intravenously. It is also a weak inhibitor of serotonin reuptake transporter (SERT) by a direct, non-opioid receptor mechanism.
Storage conditions: Room temperature
Packaging: glass vial